Resumen:
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The plant sterol, beta-sitosterol, has been administratered to nine subjects on unrestricted diet. A sustained reduction of serum total cholesterol and a lowering of the ratio of cholesterol to lipid phosohorus ocurred. Interface by sitosterol with the absorption of cholesterol, both dietary and that excreted into the gastrointestinal tract, is presumably responsible for this hypocholesterolemic effects. No toxic or undesirable side effects were observed. A meand of studying the effects of a sustained lowering of serum cholesterol on atherosclerotic states would now seem to be available.
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