Título:
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Retention-optimization strategy for the high-performance liquid chromatographic ion-pair separation of samples containing basic compounds
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Autores:
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GOLDBERG, A. P. ;
NOWAKOWSKA, E. ;
ANTLE, P. E.
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Tipo de documento:
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texto impreso
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ISBN/ISSN/DL:
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2417
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Nota general:
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ISBN:
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Langues:
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Inglés
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Clasificación:
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S (Separata)
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Resumen:
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A simple is developed to explain sample retention in ion-pai high-performance liquid chromatographic systems when pH is varied. Comparison of the model with literature data shows general agreement. On the basic of this model we propose a retention-optimization scheme for the separation of basic samples via ionpair chromatography. The data-collection procedure is the same as the described by J. L. Glajch, J. J. Kirkland, K. M. Minor (J. Chromatogr., 199 (1980) 57) for four-solvent optimization of reversed-phase separations (mixture-design technique). Application of this approach to several representative sample resulted in rapid optimization of retention and successful separation.
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Nota de contenido:
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En: Journal of Chromatography 316 241-260 (1984)
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