| Título: | Heterologous protein production in the yeast Kluyveromyces lactis |
| Autores: | ALBERT J.J. VAN OOYEN, Autor ; PETER DEKKER, Autor ; MICHAEL HUANG, Autor ; MAURIEN M.A. OLSTHOORN, Autor ; DENISE I. JACOBS, Autor ; PAUL A. COLUSSI, Autor ; CHRISTOPHER H TARON, Autor |
| Tipo de documento: | texto impreso |
| ISBN/ISSN/DL: | 68227 |
| Dimensiones: | pp. 381-392 |
| Nota general: | En: FEMS Yeast Res6(2006) 381–392 |
| Langues: | Inglés |
| Clasificación: | |
| Resumen: |
Kluyveromyces lactis is both scientifically and biotechnologically one of the most
important non-Saccharomycesyeasts. Its biotechnological significance builds on its history of safe use in the food industry and its well-known ability to produce enzymes like lactase and bovine chymosin on an industrial scale. In this article, we review the various strains, genetic techniques and molecular tools currently available for the use ofK. lactisas a host for protein expression. Additionally, we present data illustrating the recent use of proteomics studies to identify cellular bottlenecks that impede heterologous protein expression. |
