| Título: | Determination of folic acid in tablets by microemulsion electrokinetic chromatography |
| Autores: | AURORA-PRADO, MARIA S. ; SILVA, CLAUDINEI A. ; TAVARES, MARINA F. M. ; KEVIN D. ALTRIA |
| Tipo de documento: | texto impreso |
| ISBN/ISSN/DL: | 39060 |
| Nota general: | ISBN: |
| Langues: | Inglés |
| Resumen: | A microemulsion electrokinetic chromatography (MEEKC) method has been developed and validated for the determination of folic acid, a water-soluble vitamin, in a commercial tablet formulation. The analysis was performed using a microemulsion containing 0.5% (w/w) ethyl acetate, 1.2% (w/w) butan-1-ol, 0.6% (w/w) sodium dodecyl sulfate, 15% (v/v) 2-propanol and 82.7% (w/w) 10 mmol L1 sodium tetraborate aqueous buffer at pH 9.2. Direct UV detection at 214 nm led to an adequate sensitivity without interference from sample excipients. For quantitative purposes, niacin was used as internal standard. Acceptable precision ( |
| Nota de contenido: | En: Journal of Chromatography A. -- (1051) : 291-296 (2004) |
Documentos electrónicos (1)
 29182 Adobe Acrobat PDF |
